Thermo Fisher Scientific DBI Recombinant Rabbit Monoclonal Antibody (2N0A7)
Thermo Fisher의 Recombinant Rabbit Monoclonal Antibody (2N0A7)은 인간 DBI 단백질을 표적으로 하는 항체로, Western blot과 ELISA에 적합합니다. 고순도의 Protein A 정제 항체이며, 안정적인 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2N0A7 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–104 of human DBI |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.01 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
MWGDLWLLPP ASANPGTGTE AEFEKAAEEV RHLKTKPSDE EMLFIYGHYK QATVGDINTE RPGMLDFTGK AKWDAWNELK GTSKEDAMKA YINKVEELKK KYGI
Target Information
This gene encodes diazepam binding inhibitor (DBI), a protein regulated by hormones and involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors in brain synapses.
The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues forming the hydrophobic binding site for medium- and long-chain acyl-CoA esters.
DBI also mediates feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, and serves as a mediator in corticotropin-dependent adrenal steroidogenesis.
Three pseudogenes are located on chromosomes 6, 8, and 16. Multiple transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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