Thermo Fisher Scientific MCK10 Recombinant Rabbit Monoclonal Antibody (8R8Z4)
Recombinant rabbit monoclonal antibody recognizing MCK10 (DDR1/CD167a). Validated for WB and ELISA. High specificity and purity with Protein A purification. Supplied as liquid in PBS buffer with BSA and glycerol. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8R8Z4 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 21–416 of human DDR1/MCK10/CD167a |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.49 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Target Information
DDR1 (also known as MCK10 or CD167a) is a receptor tyrosine kinase activated by collagen. It regulates cell adhesion, migration, and various cellular processes. Receptor tyrosine kinases (RTKs) are key mediators of cell communication, growth, differentiation, and metabolism. DDR1 is expressed in normal and transformed epithelial cells and activated by multiple collagen types (I–VI). It is highly expressed in epithelial tissues such as kidney, lung, gastrointestinal tract, and brain, and is overexpressed in several human tumors including breast, ovarian, esophageal, and pediatric brain cancers. The gene is located on chromosome 6p21.3 near HLA class I genes, with multiple transcript variants resulting from alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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