Thermo Fisher Scientific HRI Recombinant Rabbit Monoclonal Antibody (1G4Z2)
Recombinant rabbit monoclonal antibody targeting human HRI (EIF2AK1). Validated for WB and ELISA. Expressed in HEK293 cells and purified via Protein A. Supplied as liquid in PBS with BSA and glycerol. For research use only.
- 카탈로그번호
- MA555267
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific HRI Recombinant Rabbit Monoclonal Antibody (1G4Z2)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1G4Z2 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 337–586 of human EIF2AK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.79 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
SIVEQQLPLR RNSHLEESFT STEESSEENV NFLGQTEAQY HLMLHIQMQL CELSLWDWIV ERNKRGREYV DESACPYVMA NVATKIFQEL VEGVFYIHNM GIVHRDLKPR NIFLHGPDQQ VKIGDFGLAC TDILQKNTDW TNRNGKRTPT HTSRVGTCLY ASPEQLEGSE YDAKSDMYSL GVVLLELFQP FGTEMERAEV LTGLRTGQLP ESLRKRCPVQ AKYIQHLTRR NSSQRPSAIQ LLQSELFQNS
Target Information
EIF2AK1 (HRI) is one of four kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to decreased protein synthesis. In EIF2AK1, signaling is initiated by low levels of heme. The HRI gene is localized to 7p22, where its 3′ end slightly overlaps the 3′ end of the JTV1 gene. These genes are transcribed from opposite strands. Kinase activity is induced by low heme levels and inhibited by the presence of heme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.