
Thermo Fisher Scientific Shiga toxin 2B Monoclonal Antibody (7582)
Shiga toxin type II B 서브유닛에 특이적인 단클론 항체. ELISA에 사용 가능하며, 단백질 A로 정제된 고순도 항체. 비결합형 액상 형태로 제공되며, 4°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
- Application: ELISA
- Tested Dilution: 1:20–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bacteria |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7582 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Dry ice (international) |
| RRID | AB_2815433 |
Product Specific Information
This antibody is specific for Shiga toxin type II, B subunit (Stx-2b).
Purity is greater than 90%.
Target Information
Shiga-like toxin (verotoxin) is a toxin produced by certain strains of Escherichia coli. It is named for its similarity to the AB5-type Shiga toxin produced by Shigella dysenteriae.
There are two known types—SLT1 and SLT2. The Shiga-like toxin is associated with hemolytic-uremic syndrome (HUS).
The toxin binds to highly specific receptors on cell surfaces to enter the cell. Species such as cattle, swine, and deer, which lack these receptors, can carry toxigenic bacteria asymptomatically and shed them in feces, potentially transmitting them to humans.
Shiga-like Toxin-2 Subunit B is the non-toxic binding region that forms a pentamer upon receptor binding. It can be useful in vaccine development, antibody testing, and other functional research.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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