Thermo Fisher Scientific Profilin 1 Polyclonal Antibody
Profilin 1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 등 다양한 종에 반응하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 4°C 또는 -20°C에서 안정적으로 보관 가능.
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Thermo Fisher Scientific Profilin 1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide made to a C-terminal portion of the human protein (within residues 100–140) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.17 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 30% glycerol |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153532 |
Product Specific Information
- Suggested positive control: human brain lysate.
Target Information
Profilin is an ubiquitous small (12–15 kDa) phosphoinositides and poly-L-proline binding protein that plays a role in both signal transduction pathways and actin filament dynamics.
There are two mammalian profilins with similar biochemical properties but different expression patterns:
- Profilin I: Highly expressed in most tissues except skeletal muscle.
- Profilin II: Predominantly expressed in brain, with lower levels in skeletal muscle, uterus, and kidney.
Profilin is mainly a cytosolic protein with higher concentrations in dynamic membrane areas such as the leading edge and ruffling membranes.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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