Thermo Fisher Scientific TRAF-1 Polyclonal Antibody
TRAF-1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC(P), IP에 사용 가능. Mouse 종에 반응하며, 비결합(Unconjugated) 형태의 액상 제품. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids 51–69 of mouse TRAF1 (GenBank no. NP_033447.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2718770 |
Target Information
The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins mediate signal transduction from various TNFR superfamily receptors. TRAF1 and TRAF2 form a heterodimeric complex required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. This complex also interacts with inhibitor-of-apoptosis proteins (IAPs), mediating anti-apoptotic signaling from TNF receptors. Expression of this protein can be induced by Epstein-Barr virus (EBV), and its interaction with EBV LMP1 is thought to link B lymphocyte transformation to TNFR signaling. Three transcript variants encoding two isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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