Thermo Fisher Scientific IL-3 Monoclonal Antibody (OTI5G7H9), TrueMAB

Applications

Tested Application

• Western Blot (WB): 1:1,000

Product Specifications

Product Specific Information

• For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
• For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

Interleukin 3 (IL-3), also known as Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells, and eosinophils.
IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell, and monocytic lineages.
These functions are often enhanced by co-stimulation with other cytokines.

Human and mouse IL-3 share only 29% sequence identity at the amino acid level, and IL-3 bioactivity is highly species-specific — human IL-3 shows no activity on mouse cells.
IL-3 supports proliferation and differentiation of diverse hematopoietic cell types and is involved in cell growth, differentiation, apoptosis, and may also possess neurotrophic activity linked to neurologic disorders.

For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.