Thermo Fisher Scientific Carboxypeptidase A1/CPA1 (Pancreatic Cancer Marker) Monoclonal Antibody (rCPA1/8688)
Pancreatic cancer marker CPA1에 특이적인 mouse monoclonal antibody. Western blot 및 IHC(P, PFA)에서 검증됨. Recombinant full-length human CPA1을 immunogen으로 사용. Protein A/G로 정제된 액상형 항체로, 4°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific Carboxypeptidase A1/CPA1 (Pancreatic Cancer Marker) Monoclonal Antibody (rCPA1/8688)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rCPA1/8688 |
| Immunogen | Recombinant full-length human CPA1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CPA1 (Carboxypeptidase A1), also known as CPA, is a 419 amino acid secreted monomeric protein highly expressed in pancreatic tissue. It functions as a pancreatic exopeptidase using zinc as a cofactor to catalyze the release of C-terminal amino acids from various proteins, playing a key role in protein digestion and degradation. CPA1 may also participate in zymogen inhibition, potentially blocking enzyme activation pathways. Abnormal CPA1 levels are associated with pancreatic cancer, indicating a role in tumor progression or suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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