Thermo Fisher Scientific SRPX2 Polyclonal Antibody
SRPX2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC/IF에 사용 가능하며 인간, 생쥐, 랫트 반응성. 액상 형태로 PBS/glycerol buffer에 보관되며 -20°C에서 저장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SRPX2 (Accession O60687), corresponding to amino acid residues G131–P181 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854109 |
Product Specific Information
This antibody detects endogenous levels of total SRPX2.
Target Information
Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain. Mutations in this gene can lead to epilepsy, speech dyspraxia, mental retardation, and cognitive disorders. SRPX2 has been identified as a novel mediator of angiogenesis and acts as a ligand for the urokinase-type plasminogen activator, facilitating endothelial cell migration. Overexpression of SRPX2 in gastric cancer is associated with increased phosphorylation of focal adhesion kinase, enhanced cell migration and adhesion, suggesting SRPX2 as a potential therapeutic target in metastatic cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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