Thermo Fisher Scientific GPR68 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1363)
Recombinant alpaca monoclonal antibody targeting human GPR68. Compatible with direct ELISA assays. Purified via metal-chelate chromatography, supplied as liquid at 1 mg/mL in PBS without preservative. Suitable for research use only, not for diagnostic ...
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Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1363 |
| Immunogen | Recombinant Human GPR68 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
GPR68 (also known as OGR1 - ovarian cancer G-protein coupled receptor 1) is a proton-sensing receptor involved in pH homeostasis. It acts as an osteoblastic pH sensor regulating the cell-mediated response to acidosis in bone. GPR68 mediates its action through G proteins that stimulate inositol phosphate (IP) production or Ca²⁺ mobilization. The receptor is nearly silent at pH 7.8 but fully activated at pH 6.8. It also functions as a tumor suppressor in prostate cancer. Mutations in the gene can result in amelogenesis imperfecta, hypomaturation type 2A6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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