Thermo Fisher Scientific Vimentin VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1226)
Thermo Fisher Scientific의 Vimentin VHH-8His-Cys-tag 항체는 알파카 유래 재조합 단일클론 항체로, 인간 Vimentin 단백질을 특이적으로 인식합니다. Western blot, ICC/IF, ELISA, SPR 등 다양한 어플리케이션에 사용 가능하며, CHO 세포에서 발현된 고순도 제품입니다.
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Applications
- Western Blot (WB): Assay-dependent
- Immunocytochemistry (ICC/IF): Assay-dependent
- ELISA: Assay-dependent
- Surface Plasmon Resonance (SPR): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1226 |
| Immunogen | Recombinant Human VIM/Vimentin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is believed to be involved in intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFPs, vimentin is expressed along with desmin during early cellular development and later replaced by tissue-specific IFPs.
Vimentin plays a role in steroid synthesis by acting as a storage network for cholesterol-containing lipid droplets. Phosphorylation of vimentin by protein kinases leads to intermediate filament breakdown and cytoskeletal reorganization, facilitating lipid droplet interaction with mitochondria and enhancing steroidogenic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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