Thermo Fisher Scientific Neurogenic locus notch homolog protein 1 Polyclonal Antibody
인간, 생쥐, 랫트 반응성의 Notch1 폴리클로날 항체로 다양한 면역학적 분석(WB, IHC, ICC, Flow, ELISA)에 사용 가능. KLH 결합 합성 펩타이드로 면역화된 Rabbit IgG 항체이며 Protein A로 정제됨. 액상 형태로 −20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Notch1 intracellular domain (amino acids 1754–1800) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Notch gene family encodes transmembrane proteins with multiple cysteine-rich EGF-like repeats in the extracellular region. Four Notch genes (Notch1, Notch2, Notch3, Notch4) have been identified in mammals and are involved in nervous system differentiation and other developmental processes. EGF-like proteins Delta and Serrate act as ligands for Notch1. Mature Notch proteins are heterodimeric receptors formed by cleavage into an extracellular subunit (NEC) and a transmembrane subunit (Ntm) containing the intracellular domain.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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