Thermo Fisher Scientific TIMD4 Recombinant Rabbit Monoclonal Antibody (101)

Thermo Fisher Scientific TIMD4 Recombinant Rabbit Monoclonal Antibody (Clone 101)

Applications

• ELISA (ELISA)
  Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to larger rabbit immune repertoire

This antibody specifically recognizes Human TIM4.

Target Information

The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors involved in the regulation of Th1 and Th2 cell-mediated immunity. TIM-4 is preferentially expressed on macrophages and dendritic cells and acts as the natural ligand of TIM-1, leading to T-cell expansion and cytokine production.

Unlike other TIM family members, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with asthma predisposition in both mice and humans and may be considered a candidate disease/predisposition gene for asthma.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지: MA5-31236_TIM-4_TIMD4_Q96H15-1_Rabbit.svg)
(이미지: MA5-31236_TIM-4_TIMD4_Q96H15-1_Rabbit_PDP.jpeg)