Thermo Fisher Scientific CD207 (Langerin) Polyclonal Antibody
사람, 마우스, 랫트 반응성의 CD207(Langerin) 폴리클로날 항체. Western blot과 ELISA에 적합하며, 막 단백질 Langerin 검출에 사용. 친화 크로마토그래피로 정제된 액상 항체로, -20°C 보관. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 70–200 of human Langerin/CD207 (NP_0565324) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.52 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914582 |
Product Specific Information
- Positive test controls: A-549, A-431, Jurkat, Mouse lung, Rat lung, Rat liver
- Localization: Membrane, Single-pass type II membrane protein
Immunogen sequence:
TISDVKTNVQ LLKGRVDNIS TLDSEIKKNS DGMEAAGVQI QMVNESLGYV RSQFLKLKTS VEKANAQIQI LTRSWEEVST LNAQIPELKS DLEKASALNT KIRALQGSLE NMSKLLKRQN DILQVVSQGW K
Target Information
Langerin (CD207) is a type II membrane-associated C-type lectin expressed exclusively by Langerhans cells. It recognizes mannose residues via its carbohydrate recognition domain (CRD). Langerin is localized on the cell surface and intracellularly in association with Birbeck granules. Expression of Langerin cDNA induces membrane structures characteristic of Birbeck granules, contributing to membrane superimposition and BG formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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