Thermo Fisher Scientific CST1 Polyclonal Antibody
Thermo Fisher Scientific의 CST1 Polyclonal Antibody는 인간 CST1 단백질을 인식하는 토끼 IgG 항체로, Western blot 및 ELISA 실험에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태, 안정적인 PBS/glycerol 저장용액 구성으로 연구용에 최적화되어 있습니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 20–141 of human CST1 (NP_001889.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.75 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914584 |
Product Specific Information
- Positive test controls: A-431, A-549, BT-474, THP-1
- Localization: Secreted
Immunogen sequence:
AWSPKEEDRI IPGGIYNADL NDEWVQRALH FAISEYNKAT KDDYYRRPLR VLRARQQTVG GVNYFFDVEV GRTICTKSQP NLDTCAFHEQ PELQKKQLCS FEIYEVPWEN RRSLVKSRCQ ES
Target Information
The cystatin superfamily is a well-established family of cysteine protease inhibitors.
Cystatins A and B (type 1) are mainly intracellular; cystatins C, D, E/M, F, G, S, SN, and SA are extracellular (type 2); and kininogens are type 3 cystatins which are intravascular proteins.
All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, and some also inhibit legumain family enzymes.
Cystatin SA, S, and SN are found primarily in saliva, but can also be expressed in tears, urine, and seminal fluid.
Cystatin C is expressed in brain, thymus, ovary, epididymis, and vas deferens.
Cystatin D protects against proteinases in the oral cavity, while Cystatin E/M and F moderate inhibition of cathepsin proteins.
Fetuins, part of the cystatin superfamily, are secretable proteins influencing osteogenesis, bone resorption, insulin and hepatocyte growth factor receptor regulation, and systemic inflammation response.
High and low molecular weight kininogens inhibit thrombin- and plasmin-induced aggregation of thrombocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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