Thermo Fisher Scientific TACR1 Polyclonal Antibody
TACR1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, Flow Cytometry 등에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체이며, PBS buffer에 0.02% sodium azide 포함. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 10 µg/mL |
| Immunohistochemistry (Frozen) (IHC-F) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:10–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A peptide derived from the N-terminus region between amino acids 1–50 of human Neurokinin 1 Receptor (UniProt# P25103) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2200752 |
Product Specific Information
- The target sequence has 94% sequence homology with guinea pig.
- Suggested positive control: antigen standard for TACR1 (transient overexpression lysate), SF9 whole cell membrane extracts.
Target Information
Tachykinin Receptor 1 (TACR1), also known as Neurokinin 1 Receptor, is a member of the Tachykinin Receptor subfamily. It mediates phosphatidylinositol metabolism via the tachykinin substance P. TACR1 is associated with depression, anxiety, and stress regulation, as well as neuronal survival and cardiovascular and respiratory function control. It is implicated in rheumatoid arthritis and osteoarthritis progression. Two alternatively spliced variants exist. Expression is primarily in brain, blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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