Thermo Fisher Scientific PTBP1 Recombinant Rabbit Monoclonal Antibody (ARC0783)
PTBP1 단백질을 표적하는 Thermo Fisher의 재조합 토끼 단일클론 항체. Western blot, IHC, ICC/IF, ELISA에 적합하며 인간, 마우스, 랫트 시료에 반응. 고순도 Affinity Chromatography 정제, 안정한 PBS/glycerol buffer 보존.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:6,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:800 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0783 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human PTBP1 (UniProt ID: P26599) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.22 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849275 |
Product Specific Information
Immunogen sequence:
MDGIVPDIAV GTKRGSDELF STCVTNGPFI MSSNSASAAN GNDSKKFKGD SRSAGVPSRV IHIRKLPIDV TEGEVISLGL PFGKVTNLLM LKGKNQAFIE
Target Information
The PTBP1 gene encodes a member of the heterogeneous nuclear ribonucleoproteins (hnRNPs) subfamily, which are RNA-binding proteins that associate with heterogeneous nuclear RNA (hnRNA). These proteins influence pre-mRNA processing, mRNA metabolism, and transport. PTBP1 contains four quasi-RNA recognition motif (RRM) domains that bind RNA and interact with intronic polypyrimidine tracts required for pre-mRNA splicing. It may also facilitate U2 snRNP binding to pre-mRNAs and is localized mainly in the nucleoplasm and perinucleolar structures. Multiple alternatively spliced transcript variants exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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