Thermo Fisher Scientific MEK7 Monoclonal Antibody (4E5)
인간 MAP2K7 단백질을 인식하는 Thermo Fisher MEK7 단클론 항체(4E5). Western blot, IHC, ICC/IF, Flow cytometry, ELISA 등 다양한 응용에 적합. 비결합형 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적 유지.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4E5 |
| Immunogen | Purified recombinant fragment of human MAP2K7 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% Sodium Azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet Ice |
| RRID | AB_11153789 |
Product Specific Information
MA5-15925 targets MAP2K7 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human MAP2K7 expressed in E. coli.
MA5-15925 detects MAP2K7, which has a predicted molecular weight of approximately 48 kDa.
Target Information
The protein encoded by this gene is a dual specificity protein kinase belonging to the MAP kinase family.
It specifically activates MAPK8/JNK1 and MAPK9/JNK2, and is phosphorylated and activated by MAP kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK.
This kinase mediates signal transduction in response to proinflammatory cytokines and environmental stress.
Multiple alternatively spliced transcript variants exist, but only one has been supported and defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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