Thermo Fisher Scientific ROR gamma Monoclonal Antibody (4G419)
ROR gamma 단일클론 항체(4G419)는 인간, 생쥐, 랫트 반응성을 가지며 Western blot 및 유세포분석에 적합합니다. 단백질 A/G로 정제된 액상 항체로, PBS 및 sodium azide 포함. ROR gamma 관련 면역조직 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 5 µg/mL
- View 1 publication
Flow Cytometry (Flow)
- Tested Dilution: 0.25–0.5 µg per million cells
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4G419 |
| Immunogen | A portion of amino acids 1–50 of human ROR gamma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2537745 |
Target Information
ROR gamma is a 560 amino acid DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. It acts as a ligand-activated transcription factor, essential for lymphoid organogenesis (lymph nodes and Peyer’s patches), and plays a regulatory role in apoptosis during thymopoiesis. ROR gamma inhibits Fas ligand and IL2 expression and directs differentiation of proinflammatory IL-17⁺ T helper cells. It shares 50–51% sequence identity with RORA and RORB, and is 88% identical to mouse ROR gamma. Highly expressed in skeletal muscle and lower levels in other tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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