Thermo Fisher Scientific MyD88 Monoclonal Antibody (4D6)

Applications

Tested Dilution

Publications

Western Blot (WB)

2 µg/mL

View 1 publication 1 publication

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

5 µg/mL

-

Flow Cytometry (Flow)

0.5 µg per million cells

-

Product Specifications

Species Reactivity

Human, Mouse, Non-human primate, Rhesus monkey

Published species

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

4D6

Immunogen

A portion of amino acids 50-100 of human MyD88 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MyD88,uniProtId:Q99836-1,ncbiNodeId:9606,antigenRange:50-100,antigenLength:296,antigenImageFileName:MA5-16231_MyD88_Q99836-1_House_mouse.svg,antigenImageFileNamePDP:MA5-16231_MyD88_Q99836-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.0 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2537749

Target Information

Myeloid differentiation Marker 88 (MyD88) is an adaptor molecule for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS. MyD88 recruits IRAK to IL-1 receptor complex in response to IL-1. This pathway further leads to activation of NF-kB. MyD88 has a wide tissue distribution.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.