Thermo Fisher Scientific TFB2M Polyclonal Antibody
TFB2M 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 Immunocytochemistry에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS 기반 용액 형태로 제공되며, 연구용으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human TFB2M (Recombinant protein control fragment, Product #RP-104590) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2664765 |
Product Specific Information
- Immunogen sequence:
GRFCILGSEAA TRKHLPARNH CGLSDSSPQL WPEPDFRNPP RKASKASLDF KRYVTDRRLA ETL - Highest antigen sequence identity to orthologs:
Mouse 34%, Rat 36%
Target Information
S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop.
Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM.
Stimulates transcription independently of the methyltransferase activity.
Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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