Thermo Fisher Scientific LPAR4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human LPAR4 (GPR23). Validated for IHC (Paraffin) application at 4 µg/mL. Recognizes EDG4 involved in lysophospholipid signaling and cellular growth responses. Supplied as liquid, 1 mg/mL, unconjugated, for research...
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Thermo Fisher Scientific LPAR4 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from 3rd cytoplasmic domain of human GPR23 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2135543 |
Product Specific Information
PA1-32651 detects GPR23 from human samples.
Target Information
EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. There are eight known members of the EDG receptor family, implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions dependent on cytoskeletal responses such as contraction, secretion, adhesion, and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor, and leukocyte-containing tissues.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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