Thermo Fisher Scientific ZP4 Polyclonal Antibody
Human ZP4 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:1,000–1:2,500 희석 비율로 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZP4. Recombinant protein control fragment (Product #RP-90149). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2650391 |
Product Specific Information
Immunogen sequence:
FAVNLNQEAT SPPVLIAWDN QGLLHELQND SDCGTWIRKG PGSSVVLEAT YSSCYVTEWD SHYIMPVGVE GAGAAEHKVV TERKLLKCPM DLLARDAPDT DWCDSIPA
Highest antigen sequence identity to the following orthologs:
- Mouse: 23%
- Rat: 54%
Target Information
The mammalian zona pellucida is composed of four major glycoproteins: ZP1, ZP2, ZP3, and ZP4, which may act as sperm receptors.
Two forms of porcine ZP4 peptides exist: one consisting of 128 amino acids and the other of 133 amino acids. These two peptides are identical except the larger form contains an additional five amino acids at its carboxy-terminal end.
Both peptides have two potential N-linked glycosylation sites. The smaller peptide shares 39.1% identity with the amino-terminal region of mouse ZP2 polypeptide.
Based on animal studies, ZP4 antigen is a promising candidate for the development of a contraceptive vaccine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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