Thermo Fisher Scientific ECRG4 Polyclonal Antibody
Human ECRG4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 세포 노화 및 증식 억제 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ECRG4. Recombinant protein control fragment (Product # RP-90147) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640878 |
Product Specific Information
Immunogen sequence:
KREAPVPTKT KVAVDENKAK EFLGSLKRQK RQLWDRTRPE VQQWYQQFLY MGFDEAKFED DITYWLNRDR NGHEYYGDYY QRHYDEDSAI GPRSPYGFRH GASVNYD
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 84%
- Rat: 85%
Target Information
Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system.
ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation, and accelerated CCND1 and CCND3 proteasomal degradation.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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