
Thermo Fisher Scientific Angiotensin II Receptor Type-1 (extracellular) Polyclonal Antibody, Atto 550
인간, 마우스, 랫트에 반응하는 Angiotensin II 수용체 Type-1(Extracellular) 폴리클로날 항체. Atto 550 형광 표지로 IHC, ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:60 |
| Immunocytochemistry (ICC/IF) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | NSSTEDGIKRIQDDC, corresponding to amino acid residues 4–18 of human AT1, Extracellular, N-terminus |
| Conjugate | Atto™ 550 |
| Excitation / Emission Max | 554 / 575 nm |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 50 µL of double-distilled water (DDW), depending on sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, prepare small aliquots and store at -20°C.
Avoid multiple freeze/thaw cycles. Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
Gene: AGTR1 (Angiotensin II Type 1 Receptor)
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion.
It plays a key role in controlling blood pressure and volume in the cardiovascular system, acting through at least two receptor types.
AGTR1 mediates the major cardiovascular effects of angiotensin II and may contribute to reperfusion arrhythmias following restoration of blood flow to ischemic myocardium.
Multiple alternatively spliced transcript variants have been reported for this gene.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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