
Thermo Fisher Scientific Angiotensin II Receptor Type-2 (extracellular) Polyclonal Antibody, Atto 488
Atto 488 형광 표지를 가진 Angiotensin II Receptor Type-2 (extracellular) 폴리클로날 항체로, 쥐 및 생쥐 시료에 반응합니다. IHC(F) 및 ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 혈압 및 신장 발달 관련 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Frozen) (IHC (F)) | 1:60 |
| Immunocytochemistry (ICC/IF) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | DNLNATGTNESAFNC, corresponding to amino acid residues 21–35 of rat AT2 receptor, extracellular, N-terminus |
| Conjugate | Atto™ 488 |
| Excitation / Emission Max | 501 / 523 nm |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 50 µL double distilled water (DDW), depending on sample size.
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
- The reconstituted solution can be stored at 4°C for up to 1 week.
- For longer storage, aliquot and keep at -20°C. Avoid multiple freeze/thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two receptor types, AGTR1 and AGTR2. It plays a crucial role in blood pressure regulation and kidney development.
AGTR2, a seven-transmembrane G protein-coupled receptor (GPCR), differs from AGTR1 in signaling characteristics and is involved in neurite outgrowth induction and inhibition of cellular proliferation, as well as vasoconstriction mediation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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