Thermo Fisher Scientific TRIP11/TRIP230 Polyclonal Antibody
TRIP11/TRIP230 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제됨. 인간 시료 반응성, 액상 형태, 4°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1929 and 1979 of Human thyroid hormone receptor interactor 11 (TRIP230, 230 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa.
It is located on chromosome 14q31, a region associated with genetic alterations and thyroid hormone response abnormalities.
Trip230 interacts with Rb and thyroid hormone receptor (TR) through distinct domains:
- Complex formation with Rb occurs in a hormone-independent manner.
- Complex formation with TR is thyroid hormone-dependent.
After T3 treatment, Trip230 is phosphorylated and transported to the nucleus, suggesting phosphorylation is important for nuclear translocation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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