Thermo Fisher Scientific TRIP11/TRIP230 Polyclonal Antibody
TRIP11/TRIP230 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 Immunoprecipitation에 적합합니다. 인간 유래 항원을 기반으로 제작되었으며, 비결합(Unconjugated) 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1929 and 1979 of Human thyroid hormone receptor interactor 11 (TRIP230, 230 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa. It is located on chromosome 14q31, a region associated with genetic alterations and thyroid hormone response abnormalities. The Trip230 protein interacts with Rb and thyroid hormone receptor (TR) through distinct domains. Complex formation with Rb occurs in a hormone-independent manner, while interaction with TR is thyroid hormone-dependent. After T3 treatment, Trip230 is phosphorylated and translocated to the nucleus, suggesting phosphorylation is important for nuclear transport.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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