Thermo Fisher Scientific GGA1 Polyclonal Antibody
GGA1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 사용 가능하며, 인간, 생쥐, 랫트 반응성. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
- Publications: 참고 문헌 보기
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
- Publications: 참고 문헌 보기
Miscellaneous PubMed (Misc)
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (aa 170–220 of GAT domain, human GGA1) conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | 4°C (short term), -20°C (long term, avoid freeze/thaw). Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in rat, mouse, xenopus, and zebrafish.
- Specificity: GGA1.
Target Information
This gene encodes an apoptosis inhibitory protein that prevents apoptosis after growth factor deprivation. It suppresses E2F1-induced apoptosis and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Depletion enhances the cytotoxic effect of chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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