Thermo Fisher Scientific XRCC5 (Ku86/Ku80) (Thyroid-Lupus Autoantigen) Monoclonal Antibody (XRCC5/7317)
XRCC5(Ku86/Ku80) 단백질을 인식하는 mouse monoclonal antibody로, Western blot 및 immunohistochemistry에 적합합니다. 단백질 A/G로 정제된 액상형 항체이며, 4°C에서 보관합니다. DNA 복구 관련 연구용으로 사용됩니다.
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카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific XRCC5 (Ku86/Ku80) (Thyroid-Lupus Autoantigen) Monoclonal Antibody (XRCC5/7317)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC-PFA) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | XRCC5/7317 |
| Immunogen | Recombinant fragment (around aa300–500) of human XRCC5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The XRCC5 gene encodes the 80-kDa subunit of the Ku heterodimer protein, also known as ATP-dependent DNA helicase II or DNA repair protein XRCC5. Ku acts as the DNA-binding component of DNA-dependent protein kinase and functions with the DNA ligase IV–XRCC4 complex to repair DNA double-strand breaks via non-homologous end joining and to complete V(D)J recombination. Mutations in this gene are linked to defects in DNA repair and variations in radiosensitivity, and certain polymorphisms are associated with cancer susceptibility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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