
Thermo Fisher Scientific XRCC5 (Ku86/Ku80) (Thyroid-Lupus Autoantigen) Recombinant Rabbit Monoclonal Antibody (XRCC5/8093R)
인간 XRCC5(Ku80) 단백질을 인식하는 재조합 토끼 단클론 항체입니다. 파라핀 및 PFA 고정 조직의 면역조직화학(IHC) 분석에 적합하며, HEK293 세포에서 발현되었습니다. Protein A/G로 정제되었고 4°C에서 보관합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | XRCC5/8093R |
| Immunogen | Recombinant fragment (around aa300–500) of human XRCC5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein, also known as ATP-dependent DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase and functions together with the DNA ligase IV–XRCC4 complex in the repair of DNA double-strand breaks by non-homologous end joining and in V(D)J recombination events. A rare microsatellite polymorphism in this gene has been associated with cancer in patients of varying radiosensitivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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