Thermo Fisher Scientific Thymidine Phosphorylase/PD-ECGF (Angiogenesis Marker) Monoclonal Antibody (P-GF.44C)
Thymidine Phosphorylase/PD-ECGF 단백질을 타깃으로 한 단클론 항체로, 혈관신생 마커 연구에 적합. Western blot, IHC, IP 등 다양한 응용 가능. Human, Mouse, Rat에 반응하며 Protein A/G로 정제된 액상 형태. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunoprecipitation (IP) | 0.5–1 µg per 500 µg lysate |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | P-GF.44C |
| Immunogen | Recombinant full-length human Thymidine Phosphorylase (TP/PD-ECGF) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Thymidine Phosphorylase, also known as platelet-derived endothelial cell growth factor (PD-ECGF) or gliostatin, catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate in the presence of inorganic orthophosphate.
It functions as both a chemotactic and mitogenic factor for endothelial cells and acts as a non-heparin binding angiogenic factor found in platelets.
Additionally, it plays a role in the transformation of fluoropyrimidines—cytotoxic agents used in cancer therapy—into active cytotoxic metabolites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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