Thermo Fisher Scientific MCT2 Polyclonal Antibody
Thermo Fisher Scientific의 MCT2 폴리클로날 항체는 인간 SLC16A7/MCT2 단백질을 검출하는 연구용 항체로, WB 및 IHC(P)에서 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 고농도(2.4 mg/mL) 액상 형태로 제공. 세포 내 젖산 및 피루브산 수송 연구에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | View publication |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the C-terminal of human solute carrier family 16, member 7 (monocarboxylic acid transporter 2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635971 |
Product Specific Information
This antibody detects endogenous levels of total SLC16A7 / MCT2 protein.
Target Information
Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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