
Thermo Fisher Scientific Thioredoxin Reductase 1/TXNRD1/TRXR1 Polyclonal Antibody
Rabbit Polyclonal Antibody로 Thioredoxin Reductase 1(TRXR1)을 검출. Western blot 및 Immunoprecipitation에 적합. Unconjugated 형태, 1 mg/mL 농도. 4°C 보관, Wet ice 배송. 연구용 전용 시약.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 125 to 175 of Human Thioredoxin Reductase 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3′ UTR of selenocysteine-containing genes has a common stem-loop structure, the SECIS element, necessary for recognition of UGA as a Sec codon rather than a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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