Thermo Fisher Scientific CYP17A1 Monoclonal Antibody (OTI3D9), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:500

Product Specifications

Additional Formats

• Biotin
• Request custom conjugation

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The CYP17A1 gene encodes a cytochrome P450 enzyme involved in drug metabolism and the synthesis of cholesterol, steroids, and other lipids.
This enzyme localizes to the endoplasmic reticulum and exhibits both 17α-hydroxylase and 17,20-lyase activities, playing a key role in steroidogenic pathways producing progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens.
Mutations in CYP17A1 are associated with steroid-17α-hydroxylase deficiency, 17α-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.