Thermo Fisher Scientific CP110 Polyclonal Antibody
Rabbit polyclonal antibody against human CP110 protein. Suitable for Western blot and immunoprecipitation. Essential for centrosome duplication and ciliogenesis studies. Supplied as liquid form, unconjugated, 0.2 mg/mL concentration. For research use o...
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 962 and 1012 of human centrosomal protein 110kDa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole, thereby preventing cilia formation (PubMed:17719545, PubMed:17681131, PubMed:23486064).
Also involved in promoting ciliogenesis and may play a role in the assembly of the mother centriole subdistal appendages (SDA), affecting fusion of recycling endosomes to basal bodies during cilia formation.
Required for correct spindle formation and regulates cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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