Thermo Fisher Scientific COPS6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human COPS6. Recombinant protein control fragment (Product #RP-92864). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:COPS6,uniProtId:Q7L5N1-1,ncbiNodeId:9606,antigenRange:249-322,antigenLength:327,antigenImageFileName:PA5-60673_COPS6_Q7L5N1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-60673_COPS6_Q7L5N1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640064

Product Specific Information

Immunogen sequence: EVPFNHEILR EAYALCHCLP VLSTDKFKTD FYDQCNDVGL MAYLGTITKT CNTMNQFVNK FNVLYDRQGI GRRM

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Target Information

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.