Thermo Fisher Scientific COPS6 Polyclonal Antibody
COPS6 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)와 ICC/IF에 사용 가능. Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS 기반 완충액과 글리세롤 포함. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human COPS6. Recombinant protein control fragment (Product #RP-92864). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640064 |
Product Specific Information
Immunogen sequence:
EVPFNHEILR EAYALCHCLP VLSTDKFKTD FYDQCNDVGL MAYLGTITKT CNTMNQFVNK FNVLYDRQGI GRRM
Highest antigen sequence identity to the following orthologs:
Mouse – 100%, Rat – 100%.
Target Information
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome interacts with SCF-type E3 ubiquitin ligases and acts as a positive regulator of E3 ubiquitin ligases. This protein belongs to the translation initiation factor 3 superfamily and is involved in cell cycle regulation and may serve as a cellular cofactor for HIV-1 accessory gene product Vpr.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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