Thermo Fisher Scientific ADAMTS18 Polyclonal Antibody
인간 ADAMTS18 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:50–1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼와 40% 글리세롤에 보존. 종양 억제 관련 연구에 적합.
- 카탈로그번호
- PA560675
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ADAMTS18. Recombinant protein control fragment (Product # RP-92473) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2637663 |
Product Specific Information
Immunogen sequence:
VFVTPVEVDS AGSYISHDIL HNGRKKRSAQ NARSSLHYRF SAFGQELHLE LKPSAILSSH FIVQVLGKDG ASETQKPEVQ QCFYQGFIRN DSSSSVAVST
- Highest antigen sequence identity to orthologs: Mouse – 84%, Rat – 84%.
Target Information
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family.
ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif.
Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member.
It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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