Thermo Fisher Scientific ADAMTS18 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200

Product Specifications

Product Specific Information

Immunogen sequence:

VFVTPVEVDS AGSYISHDIL HNGRKKRSAQ NARSSLHYRF SAFGQELHLE LKPSAILSSH FIVQVLGKDG ASETQKPEVQ QCFYQGFIRN DSSSSVAVST

• Highest antigen sequence identity to orthologs: Mouse – 84%, Rat – 84%.

Target Information

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family.
ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif.
Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member.
It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.