Thermo Fisher Scientific SMARCC2 Polyclonal Antibody
인간 SMARCC2 단백질의 N-말단 펩타이드(aa 254-303)에 특이적인 rabbit polyclonal antibody. Western blot에 1 µg/mL로 검증됨. 액상 형태이며 0.5 mg/mL 농도, PBS + 2% sucrose 버퍼에 보관. -20°C에서 보관, 연구용 한정.
- 판매단위
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Thermo Fisher Scientific SMARCC2 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1 µg/mL
Publications: - [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human SMARCC2 (aa 254–303) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606478 |
Product Specific Information
Peptide sequence:
EEDYEVNDDK NPVSRRKKIS AKTLTDEVNS PDSDRRDKKG GNYKKRKRSP
Target Information
Cdc73 is a tumor suppressor probably involved in transcriptional and post-transcriptional control pathways.
Cdc73 is part of the PAF1 complex, a five-subunit protein complex composed of Paf1, Cdc73, Leo1, Rtf1, and Ctr9.
PAF1 was first purified from yeast in association with RNA polymerase II and is believed to function in transcription elongation.
The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription.
In addition to coordinating events during transcription (initiation, promoter clearance, and elongation), hPAF also coordinates events in RNA quality control.
Cdc73 may also be involved in cell cycle progression through the regulation of cyclin D1/PRAD1 expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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