Thermo Fisher Scientific FNDC4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100-1:500

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 45-167 of human FNDC4 (NP_073734.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FNDC4,uniProtId:Q9H6D8-1,ncbiNodeId:9606,antigenRange:45-167,antigenLength:234,antigenImageFileName:PA5-109735_FNDC4_Q9H6D8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109735_FNDC4_Q9H6D8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.58 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855146

Product Specific Information

Immunogen sequence: DRPPSPVNVT VTHLRANSAT VSWDVPEGNI VIGYSISQQR QNGPGQRVIR EVNTTTRACA LWGLAEDSDY TVQVRSIGLR GESPPGPRVH FRTLKGSDRL PSNSSSPGDI TVEGLDGERP LQT

Target Information

Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.