Thermo Fisher Scientific RAR gamma-1,2 Polyclonal Antibody
RAR gamma-1,2 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간, 마우스, 랫트 시료에 반응합니다. Western blot 및 ELISA에 적합하며, 핵 내 단백질 검출에 사용됩니다. 고순도의 Affinity Chromatography 정제 항체입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 168–199 of human RARG (NP_0009571) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.82 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914673 |
Product Specific Information
- Positive test controls: Mouse lung, Rat kidney
- Subcellular location: Nucleus
- Immunogen sequence: KKEVKEEGSP DSYELSPQLE ELITKVSKAH QE
Target Information
Retinoic acid, a metabolite of vitamin A, is essential for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. Retinoic acid functions through interaction with the nuclear protein retinoic acid receptor (RAR).
RAR belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins, which bind to specific DNA response elements to regulate gene expression in target cells.
RAR exists as three major subtypes: alpha, beta, and gamma.
- RAR gamma-1: Predominantly expressed in skin
- RAR gamma-2: Expressed early in embryogenesis and in embryonal carcinoma cells
RAR gamma is also known as RARD, and the corresponding gene for the retinoic acid receptor gamma 1 is NR1B3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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