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Thermo Fisher Scientific TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Monoclonal Antibody (TIMP2, 4477)
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Thermo Fisher Scientific TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Monoclonal Antibody (TIMP2, 4477)

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인간 TIMP2 단백질을 인식하는 Mouse monoclonal antibody로, IHC(P) 및 Peptide Array에 사용 가능. 단백질 A/G로 정제된 액상 형태이며, PBS(pH 7.4) 버퍼에 보존제 없이 제공. 조직 고정 및 항원 회복 조건 최적화로 높은 특이도와 재현성 제공.

카탈로그번호
7077-MSM7-P1ABX
판매단위
pk
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마지막 업데이트 2025. 08. 04. 오후 10:53
Thermo Fisher Scientific 7077-MSM7-P1ABX TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Monoclonal Antibody (TIMP2, 4477) 100 ug pk판매 단위 pk ·
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825,100원VAT 포함 907,610원

Thermo Fisher Scientific · Thermo Fisher Scientific TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Monoclonal Antibody (TIMP2, 4477)

Applications

Immunohistochemistry (Paraffin) (IHC (P))

  • Tested Dilution: 1–2 µg/mL

Peptide Array (Array)

  • Tested Dilution: Assay-dependent

Product Specifications

항목 내용
Species Reactivity Human
Host/Isotype Mouse / IgG1, kappa
Class Monoclonal
Type Antibody
Clone TIMP2, 4477
Immunogen Recombinant full-length human TIMP2 protein
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Protein A/G
Storage buffer PBS, pH 7.4
Contains No preservative
Storage conditions -20°C or -80°C if preferred
Shipping conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • For Immunohistochemistry (PFA fixed):
    Incubate antibody for 30 minutes at room temperature.
    Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.

Target Information

TIMP-1 and TIMP-2 are inhibitory enzymes of the matrix metalloproteinase family, essential for maintaining connective tissue integrity.
TIMP-2 shows high binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (MMP-2 or gelatinase A), and also binds the active form of 92 kDa Type IV collagenase (MMP-9 or gelatinase B).
It inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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