
Thermo Fisher Scientific Fibulin 1 Polyclonal Antibody
Fibulin 1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot 및 ELISA에 적합합니다. Human, Mouse, Rat 반응성이 있으며, 고순도 Affinity Chromatography로 정제된 액상 형태입니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 570–670 of human FBLN1 (NP_0019872) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.15 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806282 |
Product Specific Information
- Positive Samples: U-87MG, Mouse brain, Mouse heart, Mouse spleen, Rat liver, Rat kidney
- Cellular Location: Extracellular matrix, extracellular space
- Immunogen sequence:
RLPCHENREC SKLPLRITYY HLSFPTNIQA PAVVFRMGPS SAVPGDSMQL AITGGNEEGF FTTRKVSPHS GVVALTKPVP EPRDLLLTVK MDLSRHGTVS S
Target Information
Fibulin-1 is a modular glycoprotein component of the elastic extracellular matrix fibers, basement membranes, and blood. It self-associates and binds to calcium, fibronectin, laminin, nidogen, and fibrinogen. These interactions contribute to its association with basement membranes, connective tissue, elastic fibers, and fibrin clots. Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and may serve as an indicator of cancer risk or aggressiveness. It has also been linked to inhibition of cancer cell motility with increasing exposure.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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