Thermo Fisher Scientific Fibulin 1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

ELISA

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

• Positive Samples: U-87MG, Mouse brain, Mouse heart, Mouse spleen, Rat liver, Rat kidney
• Cellular Location: Extracellular matrix, extracellular space
• Immunogen sequence:
  RLPCHENREC SKLPLRITYY HLSFPTNIQA PAVVFRMGPS SAVPGDSMQL AITGGNEEGF FTTRKVSPHS GVVALTKPVP EPRDLLLTVK MDLSRHGTVS S

Target Information

Fibulin-1 is a modular glycoprotein component of the elastic extracellular matrix fibers, basement membranes, and blood. It self-associates and binds to calcium, fibronectin, laminin, nidogen, and fibrinogen. These interactions contribute to its association with basement membranes, connective tissue, elastic fibers, and fibrin clots. Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and may serve as an indicator of cancer risk or aggressiveness. It has also been linked to inhibition of cancer cell motility with increasing exposure.

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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