Thermo Fisher Scientific CD28 Polyclonal Antibody
Human CD28 단백질을 인식하는 rabbit polyclonal antibody로, Western blot 및 ELISA에 사용 가능. 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues S(75) Q Q L Q V Y S K T G F N(85) of the v-like region of human CD28 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2073703 |
Product Specific Information
PA1-23388 detects CD28 in human samples.
Target Information
CD28 antigen is a 44 kDa disulfide-linked homodimeric T cell-specific surface glycoprotein. It belongs to the immunoglobulin superfamily and is constitutively expressed on most peripheral blood T lymphocytes. CD28 serves as a critical T cell costimulatory receptor, providing a secondary activation signal by binding to CD80 and CD86 on antigen-presenting cells. It also prevents T cells from entering an anergic or apoptotic state. CD28 expression varies across T cell developmental stages and is associated with diseases such as mycosis fungoides and Sezary’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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