Thermo Fisher Scientific XPB Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide corresponding to the carboxy-terminus of human XPB. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:XPB,uniProtId:P19447-1,ncbiNodeId:9606,antigenRange:782,antigenLength:782,antigenImageFileName:PA1-23344_XPB_P19447-1_Rabbit.svg,antigenImageFileNamePDP:PA1-23344_XPB_P19447-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2098019

Product Specific Information

Recommended positive controls: HeLa Nuclear extract.

Target Information

The human XPB DNA helicase is a subunit of the DNA repair/basal transcription factor TFIIH, and is involved in early steps of the nucleotide excision repair (NER) pathway. Two distinct clinical phenotypes, xeroderma pigmentosum associated with Cockayne`s syndrome (XP/CS) and trichothiodystrophy (TTD), can be due to mutations in the XPB gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.