Thermo Fisher Scientific Angiotensinogen Polyclonal Antibody
Thermo Fisher Scientific의 Angiotensinogen Polyclonal Antibody는 Mouse 및 Rat 시료에 반응하는 Rabbit IgG 기반 항체로, Western blot에 적합합니다. 합성 펩타이드 면역원으로 제작되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a sequence at the N-terminus of mouse Angiotensinogen (25–36aa DRVYIHPFHLLY) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745857 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The AGT gene encodes pre-angiotensinogen (angiotensinogen precursor), primarily expressed in the liver. It is cleaved by renin in response to lowered blood pressure to produce angiotensin I, which is further processed by ACE into angiotensin II, a physiologically active enzyme. This protein plays a key role in blood pressure regulation and is implicated in essential hypertension and preeclampsia. Mutations can lead to renal tubular dysgenesis and are also associated with atrial fibrillation and inflammatory bowel disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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