Thermo Fisher Scientific IKK alpha Polyclonal Antibody
IKK alpha 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot과 Immunocytochemistry에 사용 가능. Human 반응성, 비결합형 액상 형태, 항원 친화 크로마토그래피로 정제. NF-kappa B 신호전달 연구에 적합.
- 카탈로그번호
- PA519915
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A peptide corresponding to amino acids 658–674 of human IKK alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at –20°C. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153730 |
Product Specific Information
In Western blot applications, this antibody detects a band at approximately 85 kDa.
A suggested positive control is Jurkat cell lysate.
PA5-19915 can be used with blocking peptide PEP-0041.
Target Information
CHUK (IKK alpha) is a serine/threonine kinase involved in signal transduction and cellular communication. It is part of the cytokine-activated protein complex that inhibits the NF-kappa B complex.
IKK alpha, together with IKK beta and the regulatory protein NEMO (IKK gamma), phosphorylates IkB proteins, targeting them for ubiquitin-mediated degradation.
This protein plays a key role in inflammation and cell survival processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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