Thermo Fisher Scientific USP35 Polyclonal Antibody
Thermo Fisher Scientific USP35 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하는 Rabbit IgG 폴리클로날 항체로, Western blot 및 IP에 사용됩니다. 1 mg/mL 농도의 액상 형태이며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 버퍼에 50% 글리세롤 포함, 4°C 또는 -20°C에서 보관합니다.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- View 1 publication
Immunoprecipitation (IP)
- Tested Dilution: –
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in human USP35 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553974 |
Product Specific Information
This antibody detects endogenous USP35 protein at a molecular weight of approximately 113 kDa.
Purity is >95% by SDS-PAGE.
Target Information
p73 protein is a member of the p53 family of proteins. The tumor-suppressor protein p53 exhibits sequence-specific DNA binding, interacts with various cellular and viral proteins, and induces cell cycle arrest in response to DNA damage.
In response to genotoxic stresses such as UV irradiation or DNA damage, p53 accumulates in the nucleus through post-translational modifications. Activation of p53 leads to cell cycle arrest or apoptosis, preventing proliferation of genetically damaged cells.
Thus, p53-dependent pathways maintain genomic stability by eliminating damaged cells, and high levels of p53 accumulation may serve as a marker for malignancy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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