Thermo Fisher Scientific RFXAP Polyclonal Antibody
RFXAP 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태로, 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human RFXAP (Recombinant protein control fragment, Product #RP-105877) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662003 |
Product Specific Information
Immunogen sequence:
NVKLEESADNI LSIVKQRTGS FGDRPARPTL LEQVLNQKRL SLLRSPEVVQ FLQKQQQLLN QQVLEQRQQQ FPGT
- Highest antigen sequence identity to the following orthologs: mouse 96%, rat 96%.
Target Information
Major histocompatibility (MHC) class II molecules are transmembrane proteins that play a central role in immune system development and regulation.
The RFXAP protein, together with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of MHC class II gene promoters to activate transcription.
This complex also interacts with the non-DNA-binding MHC class II transactivator, determining cell type specificity and inducibility of MHC class II gene expression.
Mutations in this gene are associated with bare lymphocyte syndrome type II, complementation group D.
Transcript variants utilizing different polyA signals have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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