Thermo Fisher Scientific SAE1 Polyclonal Antibody
Human SAE1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, ELISA, IP 등 다양한 응용에 적합. 보존제가 포함되지 않아 필요 시 sodium azide 첨가 권장. 단백질 SUMO화 연구 및 SAE1 관련 단백질 기능 분석에 유용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 0.5–2 µL/mg of lysate |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human SAE1 protein (Met1–Lys346) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788250 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human SAE1.
Target Information
Posttranslational modification of proteins by the addition of the small protein SUMO (sumoylation) regulates protein structure and intracellular localization. SAE1 and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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